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Research Highlights

Hundreds of scientists working at Cold Spring Harbor Laboratory contribute research published in major research journals, in the fields of Cancer, Neuroscience, Plant Biology, Quantitative Biology, and Genomics.

Immune cells sculpt circuits in the brain

9/14/2020

Immune cells play an unexpected role in fine-tuning the brain’s neural circuits. Read the story »

an image of a section of mouse brain stained to show the insomnia

Stress, sleep, and immunity

9/9/2020

Researchers found the brain circuit that connects stress-induced insomnia and the immune system in mice. Read the story »

Understanding the inner workings of the human heart

8/19/2020

Scientists show that muscular structures first described by Leonardo da Vinci are essential for heart function. Read the story »

How to map brain connections using DNA barcodes

7/14/2020

A new technique labels brain cells with short snippets of DNA to trace many neuronal connections at a time. Read the story »

Pregnancy reprograms breast cells, reducing cancer risk

5/27/2020

CSHL researchers discovered that pregnancy reprograms breast cells, reducing the risk of breast cancer in women under 25. Read the story »

photo of Justin Kinney pointing to a model of an artificial neural network on his tablet

Finally, machine learning interprets gene regulation clearly

12/26/2019

Machine learning and a new kind of easily-interpretable artificial neural network is helping scientists make sense of crucial gene regulation. Read the story »

Shifting the balance of growth vs. defense boosts crop yield

12/19/2019

Researchers found that a specific gene in maize balances both growth of the plant and its immunity. Read the story »

BARseq builds a better brain map

10/17/2019

Created by CSHL neuroscientists, BARseq is capable of mapping connections within a brain at single-neuron resolution while tracing their gene expression. Read the story »

Mutant cells team up to make an even deadlier blood cancer

10/2/2019

Two very different mutations have been identified as unexpected partners-in-crime for causing the deadly blood cancer acute myeloid leukemia. Read the story »

Discovery could improve MDS cancer treatment

9/25/2019

Researchers have discovered a promising new target for treating myelodysplastic syndrome (MDS), a common and lethal blood cancer. Read the story »

Mice, like humans, fidget when deep in thought

9/24/2019

Mice seemed to fidget while making decisions, prompting neuroscientists to think more about the connection between movement and cognition. Read the story »

image of mitral cells and position chart

Quantifying how the brain smells

7/22/2019

Neuroscience researchers at CSHL are trying to figure out how the brain processes smells and what features of odors are important in that process. Read the story »

Norovirus structures could help develop treatments for food poisoning

6/11/2019

Researchers at CSHL used cryo-EM to reconstruct the structures of four different strains of human noroviruses, which cause food poisoning. Read the story »

image of brain mapped neural connections

Detailed new primate brain atlas could lead to disease insights

3/1/2019

An international effort has mapped the marmoset brain at an unprecedented level of detail, which brings us closer to understanding the human brain. Read the story »

image of NMDA receptor binding with chemical compound

Targeting ‘hidden pocket’ for treatment of stroke and seizure

1/18/2019

Researchers have identified a hidden molecular “pocket” in a special neuron receptor, which could lead to better treatments for stroke and seizures. Read the story »

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